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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COPS6 All Species: 18.79
Human Site: T161 Identified Species: 41.33
UniProt: Q7L5N1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L5N1 NP_006824.2 327 36163 T161 L N P M T K H T D L P V S V F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001100125 326 36044 T160 L N P M T K H T D L P V S V F
Dog Lupus familis XP_536866 321 35704 T155 L N P M T K H T D L P V S V F
Cat Felis silvestris
Mouse Mus musculus O88545 324 35862 T158 L N P M T K H T D L P V S V F
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6NUC2 318 35518 T152 L N P M T K H T D L P V S V Y
Zebra Danio Brachydanio rerio NP_001017768 297 33615 E139 D L P V S V F E S V I D I I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VCY3 341 38287 D175 N P L S R S V D H L P L K L F
Honey Bee Apis mellifera XP_393678 338 37998 D172 D P R P K N T D Q L S V S M Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001192086 297 33638 E139 D L P V H M F E S V I D L I N
Poplar Tree Populus trichocarpa XP_002330530 306 34249 T145 A Q K D L P V T I Y E S E L H
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8W206 317 35640 K151 P A I N H T Q K D L P V T I Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99 97.5 N.A. 97.8 N.A. N.A. N.A. N.A. 88.6 83.7 N.A. 56.8 62.7 N.A. 70
Protein Similarity: 100 N.A. 99 97.8 N.A. 98.4 N.A. N.A. N.A. N.A. 93.8 87.7 N.A. 75 76.3 N.A. 80.7
P-Site Identity: 100 N.A. 100 100 N.A. 100 N.A. N.A. N.A. N.A. 93.3 6.6 N.A. 20 20 N.A. 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 N.A. N.A. N.A. N.A. 100 33.3 N.A. 33.3 33.3 N.A. 26.6
Percent
Protein Identity: 35.4 N.A. N.A. 34.5 N.A. N.A.
Protein Similarity: 56.8 N.A. N.A. 56.5 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 28 0 0 10 0 0 0 19 55 0 0 19 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 19 0 0 10 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 46 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 19 0 46 0 10 0 0 0 0 0 10 % H
% Ile: 0 0 10 0 0 0 0 0 10 0 19 0 10 28 0 % I
% Lys: 0 0 10 0 10 46 0 10 0 0 0 0 10 0 0 % K
% Leu: 46 19 10 0 10 0 0 0 0 73 0 10 10 19 0 % L
% Met: 0 0 0 46 0 10 0 0 0 0 0 0 0 10 0 % M
% Asn: 10 46 0 10 0 10 0 0 0 0 0 0 0 0 10 % N
% Pro: 10 19 64 10 0 10 0 0 0 0 64 0 0 0 0 % P
% Gln: 0 10 0 0 0 0 10 0 10 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 10 10 10 0 0 19 0 10 10 55 0 10 % S
% Thr: 0 0 0 0 46 10 10 55 0 0 0 0 10 0 0 % T
% Val: 0 0 0 19 0 10 19 0 0 19 0 64 0 46 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 28 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _